Influence of the Glymphatic System on α-Synuclein Propagation: Role of Aquaporin-4 and the Dystrophin-Associated Protein Complex
Douglas M. Lopes, Sophie K. Llewellyn, Sheila E Bury, Jiazheng Wang, Jack A. Wells, Matthew E. Gegg, Guglielmo Verona, Mark F. Lythgoe, Ian F. Harrison
This study investigates how the glymphatic system influences α-synuclein propagation and shows that AQP4 dysfunction may contribute to Parkinson's disease pathology.
bioRxiv · Sep 11, 2024 · PreprintNeuroscience