Author

Megan M. Richters

Washington University in St. LouisORCID 0000-0002-5491-2537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kelsy C. CottoiD· 3 shared Malachi GriffithiD· 3 shared Obi L. GriffithiD· 3 shared Cody A. RamireziD· 2 shared Gavin P. DunniD· 2 shared Huiming XiaiD· 2 shared Jason KunisakiiD· 2 shared Jasreet HundaliD· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Kelsy C. CottoORCID

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3 papers

Recent·Most cited

BioinformaticsScience ImmunologyPeer-reviewedApr 7, 2023

Computational prediction of MHC anchor locations guide neoantigen identification and prioritization

Huiming Xia, Joshua F. McMichael, Michelle Becker‐Hapak…·Malachi Griffith

The paper predicts MHC anchor positions for 328 HLA alleles and shows that incorporating these improves neoantigen identification by correcting misclassified candidates in tumor samples.

30 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedMar 22, 2023

RegTools: Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer

Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu…·Malachi Griffith

RegTools identifies splice-associated variants in cancer by integrating genomic and transcriptomic data across 9,000 tumor samples, discovering 235,778 splicing events.

131 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsGenetics in MedicinePeer-reviewedOct 3, 2018

Standard operating procedure for somatic variant refinement of tumor sequencing data

Erica Kay Barnell, Peter Ronning, Katie Marie Campbell…·Obi L. Griffith

This paper establishes a standard operating procedure for manual refinement of somatic variants in tumor sequencing data to improve consistency and reproducibility.

94 citationstop 5%

whole-exome sequencingwhole-genome sequencing

𝕏 PostBluesky