MicrobiologybioRxivPreprint
Construction of a genome-wide pooled CRISPRi library as a resource for exploring the acid tolerance mechanism in Streptococcus mutans
Yaqi Chi, Chen Yuxing, Chongyang Yuan…·Yongliang Li
The paper constructs a genome-wide CRISPRi library to identify acid tolerance genes in S. mutans and finds 95 associated genes involved in metabolism, tRNA modification, and transcriptional regulation.
DOI 10.1101/2025.07.22.666072