Jacob S. Young

This study shows that ultrasound-mediated BBB modulation alone does not generate effective CNS immunity, but combining it with systemic immune activation enhances T-cell responses and improves immunotherapy efficacy.

This study identifies IL-6 as a driver of immunosuppression in glioblastoma, showing that its inhibition enhances response to immune checkpoint therapy and radiotherapy in preclinical models.

This study investigates how glioma-infiltrated cortex participates in speech processing by comparing neural activity with normal-appearing cortex using electrocorticography.

This study shows that dopamine receptor availability affects sensitivity to personal goal conflict and social influence in self-control decisions.

This study uses lesion-symptom mapping in patients with aphasia to show that visual and auditory lexical retrieval tasks share overlapping neural systems in the left lateral prefrontal cortex.

This study links dopamine D2 receptor availability in the ventral striatum to neural representations of subjective value in humans during decision-making.

This study investigates the relationship between dopamine function and reward discounting in healthy adults and clinical groups, finding no consistent association in healthy individuals but varying correlations in clinical conditions.