Author

Janice Robertson

Washington University in St. LouisORCID 0000-0002-5499-9943Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Ayush MishraiD· 1 shared Eric GelsleichteriD· 1 shared Erik K. HenzeiD· 1 shared Gladys Díaz VázqueziD· 1 shared Jacqueline J. EhrlichiD· 1 shared Toshimitsu KawateiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperBioinformatics

Ayush MishraORCID

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2 papers

Recent·Most cited

BioinformaticsProtein SciencePeer-reviewedNov 22, 2025

A LARGE-SCALE EVOLUTIONARY AND STRUCTURAL ANALYSIS OF CLC CHANNELS AND TRANSPORTERS

Ayush Mishra, Gladys Díaz Vázquez, Janice Robertson

This study uses AlphaFold2 to predict structural differences in CLC channels and transporters, expanding structural analysis beyond experimental data.

3 citations

protein structurestatistical model

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedDec 13, 2024

The C-terminal activating domain promotes Panx1 channel opening

Erik K. Henze, Jacqueline J. Ehrlich, Janice Robertson…·Toshimitsu Kawate

This paper identifies the C-terminal activating domain (CAD) as essential for Panx1 channel opening, showing how its cleavage repositions the N-terminus to reduce anion accumulation and promote ion permeability.

18 citationstop 3%

experimental assaycell signaling & trafficking