Author

Shipeng Shao

Peking UniversityORCID 0000-0002-5510-2501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Lei ChangiD· 2 shared Yingping HouiD· 2 shared Yujie SuniD· 2 shared Boxin XueiD· 1 shared Cheng LiiD· 1 shared Mengfan LiiD· 1 shared Ruifeng LiiD· 1 shared Xiaoying FaniD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

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10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Lei ChangORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 7, 2019

Chromatin-lamin B1 interaction promotes genomic compartmentalization and constrains chromatin dynamics

Lei Chang, Mengfan Li, Shipeng Shao…·Yujie Sun

This study investigates the role of lamin B1 in chromatin architecture and dynamics using imaging and Hi-C sequencing, finding that lamin B1 depletion leads to chromatin decompaction and increased inter-chromosomal interactions.

4 citations

Hi-Cexperimental assay

Synthetic BiologyACS Synthetic BiologyPeer-reviewedAug 29, 2017

Multiplexed sgRNA Expression Allows Versatile Single Non-repetitive DNA Labeling and Endogenous Gene Regulation

Shipeng Shao, Lei Chang, Yuao Sun…·Yujie Sun

This paper introduces a vector-independent method for multiplexed sgRNA expression, enabling efficient and scalable single non-repetitive DNA labeling and gene regulation in live cells.

50 citations

CRISPR screenexperimental assay