Boxin Xue

The paper introduces INF, an algorithm that integrates protein and gene level information to analyze regulatory circuits and their role in cellular responses and identity.

This study uses super-resolution imaging to show that replication origins are preferentially fired at the periphery of TADs due to chromatin re-organization linked to transcription and CTCF.

This study investigates the role of lamin B1 in chromatin architecture and dynamics using imaging and Hi-C sequencing, finding that lamin B1 depletion leads to chromatin decompaction and increased inter-chromosomal interactions.