Development of a growth coupled dynamic regulation network balancing malonyl-CoA node to enhance (2S)-naringenin synthesis in E. coli
Shenghu Zhou, Shuo‐Fu Yuan, Priya H. Nair, Hal S. Alper, Yu Deng, Jingwen Zhou
The paper develops a dynamic regulation network in E. coli to balance malonyl-CoA for enhanced (2S)-naringenin synthesis, achieving an 8.4-fold production improvement with balanced growth.
Metabolic Engineering · Sep 1, 2021Peer-reviewedSynthetic Biology