Author

Zhijun Huang

Van Andel InstituteORCID 0000-0002-5534-7576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:Hi-C· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Gerd P. PfeiferiD· 3 shared Wei CuiiD· 3 shared Adam KlaissiD· 1 shared Ishara S. RatnayakeiD· 1 shared Rabi TawiliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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3 shared papersGenomics

Gerd P. PfeiferORCID

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3 papers

Recent·Most cited

SMCHD1 loss re-wires MYOD1 enhancer nexuses and chromatin accessibility landscapes in muscle cells

Zhijun Huang, Wei Cui, Adam Klaiss, Gerd P. Pfeifer

This study shows that SMCHD1 loss disrupts enhancer organization and chromatin accessibility in muscle cells, leading to altered MYOD1 regulation and potential FSHD pathology.

bioRxiv · Feb 22, 2026 · PreprintMolecular Biology

DNA methylation landscapes in human cells and their chromatin determinants

Wei Cui, Zhijun Huang, Gerd P. Pfeifer

The paper investigates DNA methylation patterns in human bronchial epithelial cells and identifies chromatin determinants that influence their establishment.

Ageing and Cancer Research & Treatment · Dec 18, 2025Peer-reviewedGenomics

SMCHD1 maintains heterochromatin and genome compartments in human myoblasts

Zhijun Huang, Wei Cui, Ishara S. Ratnayake, Rabi Tawil, Gerd P. Pfeifer

This study shows SMCHD1 maintains heterochromatin and genome compartments in human myoblasts by anchoring heterochromatin domains and preventing epigenome modification.

bioRxiv · Jul 7, 2024 · PreprintGenomics