Adam Klaiss

This study shows that SMCHD1 loss disrupts enhancer organization and chromatin accessibility in muscle cells, leading to altered MYOD1 regulation and potential FSHD pathology.

This study develops two nanobodies that specifically target HSP-1, reducing its ATPase activity and protein folding capacity both in vitro and in vivo.

This study shows how two HSP70 chaperones in C. elegans, HSP-3 and HSP-4, have distinct and overlapping roles in ER proteostasis, affecting growth, reproduction, stress resistance, aging, and ER-Phagy.