Author

Alexander A. Khalessi

University of California San DiegoORCID 0000-0002-5559-9175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Sharona Ben‐HaimiD· 2 shared Akira NagamoriiD· 1 shared Alec Salcido· 1 shared Alexi NottiD· 1 shared Andrew M. BourhisiD· 1 shared Carly ShevinskyiD· 1 shared Carolyn O’ConnoriD· 1 shared Christopher D. BalakiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Sharona Ben‐HaimORCID

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2 papers

Recent·Most cited

Adaptive Charge Modulation Enables Focal, Selective Spinal Cord Stimulation

Ritwik Vatsyayan, Fadi Khoury, Tara S. Porter, Eleni Sinopoulou, Hadi Day, Samantha M. Russman, Rhea Montgomery‐Walsh, Kaushik Shukla, Helen Saad, Andrew M. Bourhis, Alec Salcido, Carly Shevinsky, Jihwan Lee, Karen J. Tonsfeldt, Akira Nagamori, , Shadi A. Dayeh

This study introduces Adaptive Charge Modulation (ACM) for spinal cord stimulation, achieving focal activation at deep tissue sites with reduced surface activation and muscle co-activation.

bioRxiv · Jun 18, 2026 · PreprintBioengineering

The inactive X chromosome drives sex differences in microglial inflammatory activity in human glioblastoma

Marla E. Tharp, Claudia Z. Han, Maya Talukdar, Christopher D. Balak, Conor Fitzpatrick, Carolyn O’Connor, Sebastian Preißl, Justin Buchanan, Alexi Nott, Laure Escoubet, Konstantinos Mavrommatis, Mihir Gupta, Marc S. Schwartz, Sang U Hoi, Pamela S. Jones, , David C. Page

The paper identifies sex differences in microglial inflammatory responses in glioblastoma, showing that genes on the inactive X chromosome drive these differences.

bioRxiv · Jun 6, 2024 · PreprintGenomics