GenomicsbioRxivPreprint
Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation
Ethan Ford, Matthew Grimmer, Sabine Stolzenburg…·Ryan Lister
Forcing DNA methylation onto thousands of human promoters with a zinc finger-DNMT3A fusion often fails to repress them, and the mark is quickly erased at H3K4me3-marked promoters.
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