Author

Pilar Blancafort

The University of Western AustraliaORCID 0000-0002-3881-7396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alex de MendozaiD· 1 shared Andrew Woo· 1 shared Ash W J Tie· 1 shared Cameron W. EvansiD· 1 shared Charlene Babra WaryahiD· 1 shared Christopher Wallis· 1 shared Edina WangiD· 1 shared Eleanor WoodwardiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alex de MendozaORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 27, 2026

Targeted epigenetic repression of oncogenic transcription factors via CRISPR/dCas9 locus-specific silencing

Shahama Taifour, Christopher Wallis, Edina Wang…·Pilar Blancafort

This paper develops a non-viral CRISPR/dCas9-KRAB system for epigenetic silencing of oncogenic transcription factors in Ewing Sarcoma, showing effective tumor suppression in cell line and patient-derived xenograft models.

DOI 10.64898/2026.06.27.734664

humanCRISPR screen

GenomicsbioRxivPreprintSep 20, 2017

Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

Ethan Ford, Matthew Grimmer, Sabine Stolzenburg…·Ryan Lister

Forcing DNA methylation onto thousands of human promoters with a zinc finger-DNMT3A fusion often fails to repress them, and the mark is quickly erased at H3K4me3-marked promoters.

45 citations

humanDNA methylation