BiochemistrybioRxivPreprint
Stability and DNA Methyltransferase Activity of DNMT3A are Maintained by Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation
Taishi Yonezawa, Justine C. Rutter, Raghav Ramabadran…·Margaret A. Goodell
This study identifies USP11 and SUMOylation as critical for maintaining DNMT3A stability and function, offering potential therapeutic strategies for diseases linked to DNMT3A instability.
DOI 10.1101/2025.03.05.641683