Hazel Sutherland

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

This study shows repeated disuse atrophy creates a molecular memory in skeletal muscle, leading to transcriptional resilience in young adults but increased susceptibility in aged muscle.

Adaptive time course of the skeletal muscle proteome during programmed resistance training in rats

This study quantifies skeletal muscle proteome changes over time in rats during resistance training, revealing distinct adaptation phases driven by ribosomal and mitochondrial protein dynamics.

Conserved and species-specific transcriptional responses to daily programmed resistance exercise in rat and mouse.

The paper compares transcriptional responses to resistance exercise in rats and mice, finding conserved pathways but species-specific differences in energy metabolism.

Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with WNT/planar cell polarity dysregulation.