James R. Boot

Yeast m6A reader Pho92 uses one helical hydrophobic interface in its disordered region to engage Caf40; a single L35A substitution halts m6A-transcript decay in meiosis.

This study shows repeated disuse atrophy creates a molecular memory in skeletal muscle, leading to transcriptional resilience in young adults but increased susceptibility in aged muscle.

The paper shows that bacterial metabolite HMB-PP activates human gut γδ T-cells to suppress fungal growth, but this mechanism is impaired in Crohn's disease.

The paper identifies epigenetic regulation of key pathways and novel druggable targets in glioblastoma by comparing chromatin remodelling in neoplastic and neural stem cells.

This study shows that parental rejection in owl monkeys reduces offspring survival and alters behavior, with evidence of miRNA changes potentially linking to epigenetic transmission.