Author

Morgan A. Esler

Fred Hutch Cancer CenterORCID 0000-0002-5570-385XUnclaimed ORCID profile · follow to get notified of new preprints

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Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew FavoriD· 1 shared Andrew J. BorstiD· 1 shared Andrew KubaneyiD· 1 shared Ann CarriD· 1 shared Barry L. StoddardiD· 1 shared Cameron J. GlasscockiD· 1 shared Connor WeidleiD· 1 shared David A. BakeriD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andrew FavorORCID

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1 paper

Recent·Most cited

De novo design of RNA and nucleoprotein complexes

Andrew Favor, Riley N. Quijano, Elizaveta Chernova, Andrew Kubaney, Connor Weidle, Morgan A. Esler, Ryan McHugh, Ann Carr, Yang Hsia, David Juergens, Kenneth D. Carr, Paul T Kim, Yuliya Politanska, Enisha Sehgal, Paul S. Kwon, , David A. Baker

This paper introduces a generative diffusion model for de novo design of RNA and nucleoprotein complexes, validated experimentally with SHAPE-seq and electron microscopy.

bioRxiv · Oct 1, 2025 · PreprintBiochemistry