Author

Margarita V. Brovkina

University of MichiganORCID 0000-0002-5580-5872Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:Drosophila· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. Josephine ClowneyiD· 3 shared Abbigayl E.C. BurtisiD· 1 shared Qianqian CheniD· 1 shared Rachel DuffiéiD· 1 shared Swathi YadlapalliiD· 1 shared Ye YuaniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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3 shared papersNeuroscience

E. Josephine ClowneyORCID

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Author profile →

3 papers

Recent·Most cited

Fruitless produces diverse neuronal sex differences by editing lineage-programmed chromatin landscapes

Margarita V. Brovkina, E. Josephine Clowney

The paper investigates how the Fruitless transcription factor generates sex-specific neuronal differences by interacting with lineage-programmed chromatin landscapes in Drosophila.

bioRxiv · Apr 16, 2026 · PreprintMolecular Biology

Clock-dependent chromatin accessibility rhythms regulate circadian transcription

Ye Yuan, Qianqian Chen, Margarita V. Brovkina, E. Josephine Clowney, Swathi Yadlapalli

This study shows that chromatin accessibility oscillates with the circadian cycle in Drosophila clock neurons, with distinct motifs associated with dusk and dawn accessibility, and that Period protein is essential for these rhythms.

PLoS Genetics · May 28, 2024Peer-reviewedNeuroscience

Fruitless decommissions regulatory elements to implement cell-type-specific neuronal masculinization

Margarita V. Brovkina, Rachel Duffié, Abbigayl E.C. Burtis, E. Josephine Clowney

The paper identifies regulatory elements in Drosophila fruitless neurons that are differentially accessible and controlled by FruM, revealing cell-type-specific masculinization mechanisms.

PLoS Genetics · Feb 18, 2021Peer-reviewedNeuroscience