Qianqian Chen

This study measures metabolic heat output of individual Drosophila brains to examine effects of sex, genotype, age, and disease on brain metabolism.

This paper identifies MOR-containing SWI/SNF foci as perinuclear scaffolds that gate chromatin accessibility for circadian gene regulation, revealing a spatial mechanism for converting protein oscillations into transcriptional rhythms.

The paper investigates how spatial organization of clock proteins and chromatin regulates circadian gene repression in Drosophila.

This study shows that chromatin accessibility oscillates with the circadian cycle in Drosophila clock neurons, with distinct motifs associated with dusk and dawn accessibility, and that Period protein is essential for these rhythms.