Feng Chen

The paper shows viral infection represses host genes with codon usage similar to viruses, supporting multiple hypotheses about tRNA competition during infection.

VIACOT provides a web server for interactive visualization and comparison of cell lineage trees, enabling analysis of correlations and differences in cell fate across datasets.

The paper uses single-cell transcriptomes and lineage trees to show that sub-CLTs are stereotyped across biological replicates, indicating a robust developmental program.

This paper introduces DELTA, an algorithm for aligning developmental cell lineage trees to compare similarities in developmental programs and identify cell fate transformations and evolutionary correspondences.