PhysiologybioRxivPreprint
Genetic background influences MAFAS64F-mediated diabetes penetrance in male mice
Zachary A. Loyd, Dongsoo Lee, Mallory A. Maurer…·Jeeyeon Cha
This study shows that genetic background affects disease penetrance in MafAS64F/+ male mice, with C57 background preventing dysglycemia while mixed background leads to diabetes and beta-cell senescence.
DOI 10.1101/2025.05.20.653758