Author

Garrett Reynolds

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Roland W. SteiniD· 3 shared Jeeyeon ChaiD· 2 shared Katie Colbert CoateiD· 2 shared Xin TongiD· 2 shared Alvin C. PowersiD· 1 shared Cristina HarmelinkiD· 1 shared Dongsoo LeeiD· 1 shared Emily M. WalkeriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersPhysiology

Roland W. SteinORCID

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3 papers

Recent·Most cited

MAFB is essential for the maintenance of adult human α-cell identity and glucagon secretion

Katie Colbert Coate, Jinhua Liu, Min Guo, Xin Tong, Vy M. N. Coykendall, Cristina Harmelink, Nandita Dey, Garrett Reynolds, Neha Mohanty, Regina Jenkins, Radhika Aramandla, Jeeyeon Cha, Alvin C. Powers, Patrick E. MacDonald, Seung K. Kim, Roland W. Stein

This study shows that MAFB is essential for maintaining adult human α-cell identity and function, linking its downregulation to impaired glucagon secretion and mitochondrial dysfunction in diabetes.

bioRxiv · Aug 18, 2026 · PreprintPhysiology

Genetic background influences MAFAS64F-mediated diabetes penetrance in male mice

Zachary A. Loyd, Dongsoo Lee, Mallory A. Maurer, Lizabeth Buzzelli, Jinhua Liu, Garrett Reynolds, Mark P. Keller, Jean‐Philippe Cartailler, Mark A. Magnuson, Roland W. Stein, Jeeyeon Cha

This study shows that genetic background affects disease penetrance in MafAS64F/+ male mice, with C57 background preventing dysglycemia while mixed background leads to diabetes and beta-cell senescence.

bioRxiv · May 20, 2025 · PreprintPhysiology

Defining unique structural features in the MAFA and MAFB transcription factors that control Insulin gene activity

Jeeyeon Cha, Xin Tong, Katie Colbert Coate, Min Amy Guo, Jinhua Liu, Garrett Reynolds, Emily M. Walker, Richard A. Stein, Hassane S. Mchaourab, Roland W. Stein

The paper identifies structural features in MAFA and MAFB transcription factors that influence their DNA-binding and Insulin enhancer activity through structural and functional analysis.

Journal of Biological Chemistry · Oct 30, 2024Peer-reviewedMolecular Biology