Author

Thierry Claudel

Medical University of ViennaORCID 0000-0002-5601-9830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander LercheriD· 2 shared Andreas BergthaleriD· 2 shared Anna Ohradanova‐RepiciD· 2 shared Ci ZhuiD· 2 shared Claudia Daniela FuchsiD· 2 shared Daniela HainbergeriD· 2 shared Emina HalilbasiciD· 2 shared Hannes S. J. StockingeriD· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alexander LercherORCID

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2 papers

Recent·Most cited

24-Nor-ursodeoxycholic acid counteracts TH17/Treg imbalance and ameliorates intestinal inflammation by restricting glutaminolysis in differentiating TH17 cells

Ci Zhu, Nicole Boucheron, Ramona Rîca, Valentina Stolz, Emina Halilbasic, Thierry Claudel, Osamah Al-Rubaye, Alexander Lercher, Maximilian Baumgartner, Lisa Sandner, Teresa Preglej, Marlis Alteneder, Veronika Mlitz, Claudia Daniela Fuchs, Daniela Hainberger, , Michael A Trauner

This paper shows that NorUDCA reduces TH17/Treg imbalance and intestinal inflammation by inhibiting glutaminolysis and mTORC1 signaling in TH17 cells.

bioRxiv · Feb 10, 2022 · PreprintMolecular Biology

24-Nor-Ursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation

Ci Zhu, Nicole Boucheron, André C. Müller, Peter Májek, Thierry Claudel, Emina Halilbasic, Hatoon Baazim, Alexander Lercher, Csilla Viczenczová, Daniela Hainberger, Teresa Preglej, Lisa Sandner, Marlis Alteneder, Alexandra Franziska Gülich, Matarr Khan, , Michael A Trauner

This study shows that NorUDCA modulates CD8+ T cell metabolism and function, reducing hepatic inflammation in a mouse model of immune-mediated liver disease.

Journal of Hepatology · Jul 7, 2021Peer-reviewedMolecular Biology