Maximilian Baumgartner

Gut-derived ammonia modulates hypothalamic stress responses during viral infection

This study shows that gut-derived ammonia modulates hypothalamic stress responses during viral infection by increasing corticosterone levels and affecting antiviral responses.

Host-derived bile acids drive dysbiosis by selecting bile-resistant epimerizing bacteria in inflammatory bowel disease

The paper identifies epimerized host-derived bile acids as a driver of dysbiosis in IBD by selecting for bile-resistant bacteria that disrupt host bile acid feedback signaling.

Crosstalk between CD8+ T cells and systemic bile acid metabolism controls LCMV-induced immunopathology

This study shows that CD8+ T cells and bile acid metabolism interact during LCMV infection, with bile acids affecting T cell responses and immunopathology.

24-Nor-ursodeoxycholic acid counteracts TH17/Treg imbalance and ameliorates intestinal inflammation by restricting glutaminolysis in differentiating TH17 cells

This paper shows that NorUDCA reduces TH17/Treg imbalance and intestinal inflammation by inhibiting glutaminolysis and mTORC1 signaling in TH17 cells.