PathologybioRxivPreprint
Autophagy driven by VPS34 enables differentiated cell plasticity and cancer initiation
Fernanda Ramos‐Delgado, Hala Shalhoub, Camille Guyon…·Julie Guillermet‐Guibert
This study shows that VPS34-driven autophagy restricts cancer initiation by preventing transdifferentiation and reducing oncogenic KRAS promotion in pancreatic acinar cells.