Cancer BiologybioRxivPreprint
A PTBP1-CDC42 splicing axis regulates leukemia growth and venetoclax sensitivity in acute myeloid leukemia
Margaux Oberling, Mathieu Landry, Yann Aubert…·Margherita Ghisi
This study identifies PTBP1-CDC42 splicing regulation as a critical factor in AML growth and venetoclax sensitivity, suggesting a therapeutic combination strategy.
DOI 10.64898/2026.08.25.745954