Human bone marrow adipocytes drive prostate cancer bone metastasis progression via lipid-mediated induction of Angiopoietin-like 4
Marine Hernandez, Sauyeun Shin, David Rengel, Stéphanie Dauvillier, Nancy Geoffre, Carine Valle, Alessandro Taccini, Mohamed Moutahir, Justine Bertrand‐Michel, Nicolas Reina, Catherine Muller, Camille Attané
This study identifies BMAds as drivers of prostate cancer bone metastasis through lipid-mediated induction of ANGPTL4, showing its clinical relevance as a therapeutic target.
bioRxiv · Jul 21, 2026 · PreprintCancer Biology