Systems BiologyPLoS ONEPeer-reviewed
Influence of pathway topology and functional class on the molecular evolution of human metabolic genes
Ludovica Montanucci, Hafid Laayouni, Begoña Dobón…·Juli G. Peretó
The paper analyzes the molecular evolution of human metabolic genes, finding that pathway topology and functional class influence selective pressures, with core genes being more conserved and outer layer genes more plastic.
3 citations