Jaume Bertranpetit

This study examines how immune-related traits evolved in ancient and modern European populations, finding that the Neolithic transition influenced cytokine production and disease susceptibility.

The paper shows that tissue-specific enhancers are mostly intronic and regulate genes involved in tissue-specific functions, while housekeeping genes are controlled by intergenic enhancers.

The paper analyzes the molecular evolution of human metabolic genes, finding that pathway topology and functional class influence selective pressures, with core genes being more conserved and outer layer genes more plastic.