Author

Leslie Vazquez

Duke Medical CenterORCID 0000-0002-5609-980XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert R. La SpadaiD· 1 shared Çağla EroğluiD· 1 shared Christabel Xin TaniD· 1 shared Dhanesh Sivadasan BinduiD· 1 shared Gabrielle M. SejourneiD· 1 shared Jessica L. MooreiD· 1 shared Kristina SakersiD· 1 shared Kylie Dimond· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Albert R. La SpadaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintApr 9, 2023

PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

Shiyi Wang, Ryan Baumert, Gabrielle M. Sejourne…·Çağla Eroğlu

This study shows that the LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance by hyperphosphorylating ERM proteins, which disrupts the Ezrin/Atg7 interaction and autophagy.

2 citations

mousestatistical model

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