Qiang Zhu

N-terminal Chirality and Sequence Variations Modulate the Conformational Landscape of Amyloid-beta 42

This study investigates how N-terminal chirality and sequence variations affect the conformational landscape of A{beta}42, finding that certain mutations and chiral modulations influence the central hydrophobic core and may have protective or pathogenic effects.

Structural basis of the nucleotide incorporation cycle of bacterial DNA polymerase III

This study determines cryo-EM structures of bacterial DNA polymerase III complexes to elucidate the mechanism of nucleotide incorporation and proofreading.