Synthetic BiologybioRxivPreprint
Polymerase Evolution Enables Access to Glycosylated Xeno-Nucleic Acids with Expanded Chemical Functionality
Eloi Vincent, Victoria A. Maola, Clement Lopez…·Marc H. Delarue
This paper evolves a DNA polymerase to synthesize glycosylated xeno-nucleic acids with base and backbone modifications, enabling new chemical functionality in genetic polymers.
DOI 10.64898/2026.07.20.739590