NeuroscienceJournal of Biological ChemistryPeer-reviewed
Neurodegeneration Risk Factor, EIF2AK3 (PERK), Influences Tau Protein Aggregation
Goonho Park, Ke Xu, Leon Chea…·Jonathan H. Lin
This study shows that PERK activity prevents tau aggregation and that reduced PERK signaling increases tau neuropathology in tauopathies.
23 citations