Author

Jaeseok Han

Soonchunhyang UniversityORCID 0000-0001-6402-9740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Soyoung ParkiD· 2 shared Fedho KusumaiD· 1 shared Goonho ParkiD· 1 shared Hyejung Min· 1 shared Hyo‐Wook GiliD· 1 shared Jian WuiD· 1 shared Jonathan H. LiniD· 1 shared Ke XuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Soyoung ParkORCID

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2 papers

Recent·Most cited

Mitochondrial Double-Stranded RNA Triggers Ferroptosis via PKR-ISR Signaling in Renal Ischemia-Reperfusion Injury

Richie Justin, Maria Sophia Criste, Soyoung Park, Fedho Kusuma, Nara Lee, Yerin Yang, Kim Anh Nguyen, Samel Park, 김정안, Hyo‐Wook Gil, Jaeseok Han

This study identifies mitochondrial dsRNA-PKR-ISR signaling as a driver of ferroptosis in renal ischemia-reperfusion injury, showing that targeting this pathway reduces ferroptosis and preserves kidney function.

bioRxiv · Jan 20, 2026 · PreprintCell Biology

Neurodegeneration Risk Factor, EIF2AK3 (PERK), Influences Tau Protein Aggregation

Goonho Park, Ke Xu, Leon Chea, Kyle Kim, Lance A. Safarta, Keon‐Hyoung Song, Jian Wu, Soyoung Park, Hyejung Min, Nobuhiko Hiramatsu, Jaeseok Han, Jonathan H. Lin

This study shows that PERK activity prevents tau aggregation and that reduced PERK signaling increases tau neuropathology in tauopathies.

Journal of Biological Chemistry · Dec 20, 2022Peer-reviewedNeuroscience