Author

Jyotirmayee Padhan

Indian Institute of Science Education and Research KolkataORCID 0000-0002-5639-4390Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Babu SudhamallaiD· 3 shared Soumen BarmaniD· 2 shared Sayar Ghosh· 1 shared Snehasudha S. Sahoo· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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3 shared papersBiochemistry

Babu SudhamallaORCID

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3 papers

Recent·Most cited

BiochemistryBiochemistryPeer-reviewedJul 3, 2026

Aromatic cage-directed azide-methyllysine photochemistry for profiling non-histone interacting partners of the MeCP2 methyl-CpG binding domain

Jyotirmayee Padhan, Sayar Ghosh, Soumen Barman, Babu Sudhamalla

This study identifies novel non-histone interacting partners of MeCP2 using a chemoproteomic approach with a photocrosslinkable amino acid.

DOI 10.1021/acs.biochem.6c00309

humanproteomics

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BiochemistryJournal of Biological ChemistryPeer-reviewedDec 29, 2025

Methyl-CpG Binding Protein 2 Reads Histone Methylation via an Aromatic Cage to Regulate Gene Expression and Chromatin Association

Jyotirmayee Padhan, Babu Sudhamalla

This study identifies an aromatic cage in MeCP2-MBD that binds methylated lysine residues on histone H3, showing its role in chromatin association and gene regulation.

4 citations

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BioinformaticsJournal of Biomolecular Structure and DynamicsPeer-reviewedDec 16, 2022

Identification of novel natural product inhibitors of BRD4 using high throughput virtual screening and MD simulation

Soumen Barman, Snehasudha S. Sahoo, Jyotirmayee Padhan, Babu Sudhamalla

This study identifies five natural product inhibitors of BRD4-BD1 through virtual screening and MD simulation, with three showing similar or better binding affinity than JQ1.

6 citations

statistical modeldrug response / drug discovery

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