Babu Sudhamalla

This study uses site-specific photocrosslinking to identify nonhistone proteins interacting with the TRIM24 bromodomain, revealing NPM1, CDK9, and others.

This study identifies novel non-histone interacting partners of MeCP2 using a chemoproteomic approach with a photocrosslinkable amino acid.

This study identifies an aromatic cage in MeCP2-MBD that binds methylated lysine residues on histone H3, showing its role in chromatin association and gene regulation.

This study identifies five natural product inhibitors of BRD4-BD1 through virtual screening and MD simulation, with three showing similar or better binding affinity than JQ1.