Developmental BiologybioRxivPreprint
Context-dependent response of endothelial cells to PIK3CA mutation
Helena Sabata, Ariadna Roca-Coll, Jose A. Dengra…·Mariona Graupera
This study shows that PIK3CAH1047R mutation causes clonal expansion in capillary and venous endothelial cells but not in arterial cells, revealing stage-dependent responses and a protective mechanism against arterial damage.
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