Author

Jan H.N. Lindeman

Leiden University Medical CenterORCID 0000-0002-5656-4345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

A. Stijn L. P. CrobachiD· 1 shared Alexander GuðjónssoniD· 1 shared Antoon van den Bogaerdt· 1 shared Brynjolfur G. JonssoniD· 1 shared Connie M. Janssen‐van Rhijn· 1 shared Cor J. RavensbergeniD· 1 shared Elias Freyr GudmundssoniD· 1 shared Hein PutteriD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperCancer Biology

A. Stijn L. P. CrobachORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Whole-Slide ECM Imaging Reveals Dense Fibrous Matrix as a High-Risk Factor for Recurrence in Stage II Colon Cancer

Cor J. Ravensbergen, V.S. Colaco, Hein Putter, A. Stijn L. P. Crobach, Jurjen J. Boonstra, Jan H.N. Lindeman, Rob A.�E.�M. Tollenaar, Wilma E. Mesker

The paper uses whole-slide ECM imaging to show dense fibrous matrix is linked to higher recurrence risk in Stage II colon cancer.

bioRxiv · Nov 14, 2024 · PreprintCancer Biology

The multifaceted process of human coronary atherosclerotic cap destabilisation

Laura E. Bruijn, Natascha Fonseca Neves, Connie M. Janssen‐van Rhijn, Jaap F. Hamming, Antoon van den Bogaerdt, Jan H.N. Lindeman

This study maps the qualitative changes in coronary atherosclerotic cap characteristics during lesion progression and destabilization using a pseudo-timeline approach.

bioRxiv · Jul 21, 2024 · PreprintPathology

Coding and regulatory variants affect serum protein levels and common disease

Valur Emilsson, Valborg Guðmundsdóttir, Alexander Guðjónsson, Mohd Anisul Karim, Marjan Ilkov, James R. Staley, Elias Freyr Gudmundsson, Brynjolfur G. Jonsson, Lenore J. Launer, Jan H.N. Lindeman, Nicholas M. Morton, Thor Aspelund, John R. Lamb, Lori L. Jennings, Vilmundur G. Gudnason

The paper identifies 2019 exome array variants affecting 2135 serum proteins and their association with hundreds of complex disease traits in the AGES Reykjavik cohort.

bioRxiv · May 6, 2020 · PreprintGenetics