NeurosciencebioRxivPreprint
Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations
Thomas Paß, Konrad M. Ricke, Pierre Hofmann…·Rudolf J. Wiesner
This study shows that mice with severe loss of nigral dopamine neurons due to mtDNA mutations still maintain motor function through preserved striatal innervation.
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