Author

Konrad M. Ricke

University of OttawaORCID 0000-0002-9425-0603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Haley M. GeertsmaiD· 2 shared Jean-Louis A. ParmasadiD· 2 shared Maxime W.C. RousseauxiD· 2 shared Steve M. CallaghaniD· 2 shared Alvin P. JoseliniD· 1 shared Amanda Bruce· 1 shared Andre Ferrer CarvalhoiD· 1 shared Benjamin NguyeniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Haley M. GeertsmaORCID

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3 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedApr 4, 2024

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen…·Maxime W.C. Rousseaux

This study shows that reducing CDK14 genetically or pharmacologically decreases alpha-synuclein pathology and improves symptoms in Parkinson's disease models.

10 citations

mousehuman

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NeurosciencebioRxivPreprintJul 7, 2023

Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

Thomas Paß, Konrad M. Ricke, Pierre Hofmann…·Rudolf J. Wiesner

This study shows that mice with severe loss of nigral dopamine neurons due to mtDNA mutations still maintain motor function through preserved striatal innervation.

2 citations

mousebulk RNA-seq

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NeuroscienceHuman Molecular GeneticsPeer-reviewedFeb 18, 2022

Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.

Haley M. Geertsma, Terry R. Suk, Konrad M. Ricke…·Maxime W.C. Rousseaux

38 citationstop 3%

mouseexperimental assay

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