Ruslan Soldatov

The paper identifies a genetic variant that protects against clonal hematopoiesis by regulating RNA-binding protein MSI2 in hematopoietic stem cells.

The paper identifies impaired T cell priming and KLF2-dependent quiescence in gastric cancer draining lymph nodes as mechanisms limiting immune responses.

scFates is a Python package for analyzing single-cell data trajectories, focusing on pseudotime, bifurcation, and cell fate splits, with integration into the scanpy ecosystem.

This paper introduces Numbat, a method that uses haplotype information to improve detection of copy number variations from scRNA-seq data, revealing subclonal complexity in cancer.

This paper introduces Baysor, a Bayesian segmentation tool for spatial transcriptomics data that improves cell identification and reduces contamination across multiple protocols.

The paper decomposes mutation rate and spectra variation in human germline using blind source separation, identifying nine processes including those related to DNA damage and replication timing.

Unspliced versus spliced mRNA in standard scRNA-seq gives RNA velocity, a per-cell vector predicting future state over hours, validated in neural crest and used to trace mouse hippocampal lineages.