Author
Memorial Sloan Kettering Cancer CenterORCID 0000-0001-8028-838XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Ly Vu, Zhen Jin, Brenda Ma…·Pieter R. Cullis
This study identifies PAN3-AS1 as an oncogenic lncRNA in AML, shows its role in chromatin organization, and demonstrates RNA-targeting LNP therapy to reduce leukemia burden.
Gaurav Agarwal, Mateusz Antoszewski, Xuejun Xie…·Vijay G. Sankaran
The paper identifies a genetic variant that protects against clonal hematopoiesis by regulating RNA-binding protein MSI2 in hematopoietic stem cells.
Alexandra Schurer, Humaira Ilyas, Maxim I. Maron…·David Shechter
This study identifies TTLL4 as a therapeutic target in NPM1-mutated AML by showing its role in stabilizing NPM1c and promoting differentiation block, with a small molecule inhibitor demonstrating efficacy.