Author

Evgeny Budygin

Wake Forest University School of MedicineORCID 0000-0002-5675-0279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Maria Laura MessiiD· 1 shared Osvaldo DelbonoiD· 1 shared Ragunath MuthuiD· 1 shared Savannah Longo· 1 shared Valentina GrinevichiD· 1 shared William MeekeriD· 1 shared Zhongmin WangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Maria Laura MessiORCID

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1 paper

Recent·Most cited

Spinal Noradrenergic Overdrive Promotes Reversible Motor Unit Aging and Sarcopenia

Zhongmin Wang, Valentina Grinevich, Maria Laura Messi, Savannah Longo, Ragunath Muthu, William Meeker, Evgeny Budygin, Osvaldo Delbono

This study shows that aging increases spinal noradrenergic activity, leading to motor neuron hyperexcitability and sarcopenia, which can be reversed by suppressing noradrenergic signaling.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience