Author

Govinda Sharma

Canada's Michael Smith Genome Sciences CentreORCID 0000-0002-5675-2637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Fei TengiD· 1 shared James W. RoundiD· 1 shared Robert A. HoltiD· 1 shared Sarania Sivasothy· 1 shared Scott D. BrowniD· 1 shared Sophie SneddoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Fei TengORCID

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1 paper

Recent·Most cited

Comprehensive Functional Self-Antigen Screening to Assess Cross-Reactivity in a Promiscuous Engineered T-cell Receptor

Govinda Sharma, Fei Teng, James W. Round, Sophie Sneddon, Scott D. Brown, Sarania Sivasothy, Robert A. Holt

The paper uses Tope-seq to identify cross-reactive epitopes in an engineered T-cell receptor that caused off-target toxicity, highlighting the need for comprehensive screening.

bioRxiv · May 13, 2025 · PreprintImmunology