Author

Maria A. Costa-Besada

University College LondonORCID 0000-0002-5685-1053Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessia Fisher· 1 shared Ioanna Kourouzidou· 1 shared Jialiu ZengiD· 1 shared Kritarth SinghiD· 1 shared Mark W. GrinstaffiD· 1 shared Michael R. DucheniD· 1 shared Orian S. ShirihaiiD· 1 shared Preethi SheshadriiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Alessia Fisher

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Targeting Lysosomal pH Restores Mitochondrial Quality Control in GBA1-Mutant Parkinsons Disease

Preethi Sheshadri, Maria A. Costa-Besada, Alessia Fisher, Szilvia Kiraly, Kritarth Singh, Ioanna Kourouzidou, Thomas S. Blacker, Jialiu Zeng, Orian S. Shirihai, Mark W. Grinstaff, Michael R. Duchen

This study shows that targeting lysosomal pH with rapamycin or acidic nanoparticles restores mitochondrial function in GBA1-mutant Parkinson's disease neurons.

Translational Neurodegeneration · Jun 17, 2026Peer-reviewedNeuroscience