Author

Szilvia Kiraly

University College LondonORCID 0009-0005-3641-5544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:statistical model· 1

Frequent Co-Authors

Emily R. EdeniD· 2 shared Frances M. PlattiD· 2 shared Alessia Fisher· 1 shared Andrea BallabioiD· 1 shared Andrea MartelloiD· 1 shared Antonio DE LUCA· 1 shared Christelle DuboisiD· 1 shared Germano GuerraiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Emily R. EdenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceTranslational NeurodegenerationPeer-reviewedJun 17, 2026

Targeting Lysosomal pH Restores Mitochondrial Quality Control in GBA1-Mutant Parkinsons Disease

Preethi Sheshadri, Maria A. Costa-Besada, Alessia Fisher…·Michael R. Duchen

This study shows that targeting lysosomal pH with rapamycin or acidic nanoparticles restores mitochondrial function in GBA1-mutant Parkinson's disease neurons.

5 citationstop 1%

humanbulk RNA-seq

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Cell BiologybioRxivPreprintJun 2, 2026

HKDC1 contributes to aberrant lysosome-mitochondria contact in Niemann-Pick disease type C

Raffaele Pastore, Jack Stanley, Szilvia Kiraly…·Emily R. Eden

This study establishes isogenic NPC1 and NPC2 models to reveal that HKDC1 regulates mitochondrial-lysosome contact in NPC1-deficient cells.

DOI 10.64898/2026.06.01.729255

humanproteomics

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Cell BiologybioRxivPreprintApr 27, 2025

N-Acetyl-l-Leucine (NALL) rescues inter-organelle communication in Niemann-Pick disease type-C patient cells.

Szilvia Kiraly, Andrea Martello, Frances M. Platt, Emily R. Eden

The paper shows NALL rescues inter-organelle communication and restores lysosomal and mitochondrial function in NPC patient cells.

4 citations

humanproteomics

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