Author

Alexander M. Hilla

Ruhr University BochumORCID 0000-0002-5694-3097Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Dietmar FischeriD· 2 shared Philipp GobrechtiD· 2 shared Anastasia AndreadakiiD· 1 shared Charlotte ZeitleriD· 1 shared Günter GisselmanniD· 1 shared Jeannette GebeliD· 1 shared Marco LeibingeriD· 1 shared Miriam Paulat· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Dietmar FischerORCID

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2 papers

Recent·Most cited

Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

Marco Leibinger, Charlotte Zeitler, Miriam Paulat, Philipp Gobrecht, Alexander M. Hilla, Anastasia Andreadaki, Rainer Guthoff, Dietmar Fischer

The paper shows that parthenolide, by inhibiting microtubule detyrosination, enhances axon regeneration in the CNS when combined with pro-regenerative treatments like hIL-6.

eLife · Jul 5, 2023Peer-reviewedNeuroscience

VASH1/2 inhibition accelerates functional recovery of injured nerves

Philipp Gobrecht, Jeannette Gebel, Alexander M. Hilla, Günter Gisselmann, Dietmar Fischer

This study shows that inhibiting VASH1/2 with parthenolide or its prodrug DMAPT promotes axon regeneration in injured nerves across species, suggesting potential therapeutic applications for nerve injuries.

bioRxiv · Sep 20, 2022 · PreprintNeuroscience