Author

Philipp Gobrecht

University of CologneORCID 0000-0002-9989-8927Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Dietmar FischeriD· 3 shared Alexander M. HillaiD· 2 shared Anastasia AndreadakiiD· 2 shared Charlotte ZeitleriD· 2 shared Günter GisselmanniD· 2 shared Marco LeibingeriD· 2 shared Jeannette GebeliD· 1 shared Miriam Paulat· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Dietmar FischerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

Marco Leibinger, Charlotte Zeitler, Miriam Paulat, Philipp Gobrecht, Alexander M. Hilla, Anastasia Andreadaki, Rainer Guthoff, Dietmar Fischer

The paper shows that parthenolide, by inhibiting microtubule detyrosination, enhances axon regeneration in the CNS when combined with pro-regenerative treatments like hIL-6.

eLife · Jul 5, 2023Peer-reviewedNeuroscience

VASH1/2 inhibition accelerates functional recovery of injured nerves

Philipp Gobrecht, Jeannette Gebel, Alexander M. Hilla, Günter Gisselmann, Dietmar Fischer

This study shows that inhibiting VASH1/2 with parthenolide or its prodrug DMAPT promotes axon regeneration in injured nerves across species, suggesting potential therapeutic applications for nerve injuries.

bioRxiv · Sep 20, 2022 · PreprintNeuroscience

Transneuronal delivery of designer-cytokine enables functional recovery after complete spinal cord injury

Marco Leibinger, Charlotte Zeitler, Philipp Gobrecht, Anastasia Andreadaki, Günter Gisselmann, Dietmar Fischer

This study shows that post-injury injection of hIL-6 into the sensorimotor cortex promotes axon regeneration and locomotion recovery after complete spinal cord injury by stimulating serotonergic neurons in the brain stem.

Nature Communications · Jan 15, 2021Peer-reviewedNeuroscience