Synthetic BiologybioRxivPreprint
Highly multiplexed design of an allosteric transcription factor to sense novel ligands
Kyle K. Nishikawa, Jackie Chen, Justin F. Acheson…·Srivatsan Raman
This paper introduces Sensor-seq, a high-throughput platform to design and identify allosteric transcription factor biosensors for non-native ligands, demonstrating utility with novel biosensors for naltrexone and quinine.
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