Author

Max P. C. Frenkel

University of Wisconsin–MadisonORCID 0000-0002-7208-4587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scATAC-seq· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Srivatsan RamaniD· 2 shared Brian G. FoxiD· 1 shared Daniel H. LeeiD· 1 shared Ella C. Lodewyk· 1 shared Hailey R. Sieren· 1 shared Jackie CheniD· 1 shared Jorge L. CháveziD· 1 shared Justin F. AchesoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSynthetic Biology

Srivatsan RamanORCID

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2 papers

Recent·Most cited

Highly multiplexed design of an allosteric transcription factor to sense novel ligands

Kyle K. Nishikawa, Jackie Chen, Justin F. Acheson, Svetlana V. Harbaugh, Phil Huss, Max P. C. Frenkel, Nathan Novy, Hailey R. Sieren, Ella C. Lodewyk, Daniel H. Lee, Jorge L. Chávez, Brian G. Fox, Srivatsan Raman

This paper introduces Sensor-seq, a high-throughput platform to design and identify allosteric transcription factor biosensors for non-native ligands, demonstrating utility with novel biosensors for naltrexone and quinine.

bioRxiv · Mar 7, 2024 · PreprintSynthetic Biology

Discovering chromatin dysregulation induced by protein-coding perturbations at scale

Max P. C. Frenkel, Margaux L.A. Hujoel, Zachary Scott Morris, Srivatsan Raman

The paper introduces PROD-ATAC, a method to study chromatin effects of protein-coding variants, revealing common dysregulation mechanisms across oncofusions and cancers.

bioRxiv · Sep 20, 2023 · PreprintGenomics